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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA5
All Species:
23.33
Human Site:
S149
Identified Species:
51.33
UniProt:
Q8WWZ7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWZ7
NP_061142.2
1642
186508
S149
F
P
D
M
I
P
V
S
S
I
Y
M
D
S
R
Chimpanzee
Pan troglodytes
XP_511650
1642
186524
S149
F
P
D
M
I
P
V
S
S
I
Y
M
D
S
R
Rhesus Macaque
Macaca mulatta
XP_001082244
1618
183230
D153
P
A
K
K
E
H
K
D
H
T
A
H
C
Y
E
Dog
Lupus familis
XP_537573
1642
186609
S149
F
P
D
M
I
P
V
S
S
I
Y
M
D
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K448
1642
185876
S149
F
P
E
M
I
P
V
S
S
I
Y
M
N
S
R
Rat
Rattus norvegicus
Q8CF82
1642
185792
S149
F
P
D
M
V
P
V
S
S
V
Y
M
D
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
T229
F
P
D
L
I
P
V
T
S
I
Y
M
D
S
R
Chicken
Gallus gallus
XP_415695
1646
186355
S150
P
D
M
V
A
M
A
S
V
Y
T
E
S
R
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
P147
P
Y
S
Q
L
P
L
P
S
D
F
T
E
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
G177
L
N
Y
R
I
L
L
G
K
T
P
E
E
T
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
N168
F
D
Y
S
I
R
L
N
H
T
W
A
F
A
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
42.1
93
N.A.
90
90.2
N.A.
81.3
71.5
N.A.
52
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
100
99.8
62.8
96.7
N.A.
94.8
95.1
N.A.
88
86
N.A.
70.5
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
86.6
6.6
N.A.
20
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
100
13.3
N.A.
46.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
10
0
0
0
10
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
19
46
0
0
0
0
10
0
10
0
0
46
0
0
% D
% Glu:
0
0
10
0
10
0
0
0
0
0
0
19
19
0
10
% E
% Phe:
64
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
19
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
64
0
0
0
0
46
0
0
0
0
10
% I
% Lys:
0
0
10
10
0
0
10
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
0
10
10
10
28
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
46
0
10
0
0
0
0
0
55
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
28
55
0
0
0
64
0
10
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
55
% R
% Ser:
0
0
10
10
0
0
0
55
64
0
0
0
10
64
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
28
10
10
0
10
0
% T
% Val:
0
0
0
10
10
0
55
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% W
% Tyr:
0
10
19
0
0
0
0
0
0
10
55
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _